Silence Therapeutics PLC (LON:SLN) has unveiled a deal with Takeda worth “single digit million dollars” in research funding. The Japanese pharma giant will use the UK drug developer’s platform to generate siRNA molecules targeting “undisclosed” illnesses. siRNA, which stands for small interfering ribonucleic acid, is a class of molecule that helps silence production of certain proteins, including but not limited to those associated with cancer. At the same time, the company announced plans to create a US subsidiary.

Itaconix PLC (LON:ITX) has announced the delivery of the first order of an odour control polymer to Croda International Plc (LON:CRDA) under a global supply agreement. The polymers specialist said in a statement it has delivered the first order of ZINADOR 35L, which is a more concentrated version of its proprietary polymeric complex, to the FTSE 100 listed chemicals company.

Eden Research plc (LON:EDEN) said its three EU-registered active ingredients have been approved for use in organic farming in the European Union (EU). The biopesticide products developer said the ingredients, geraniol, eugenol and thymol, got the all-clear to be used in organic farming after being included in the European Union’s Organic Production Regulation.

Woodbois Ltd (LON:WBI) said revenues increased by around 48% last year to around US$20mln after four successive record quarters from its forestry and trading businesses. The sustainable hardwood producer, which manages and operates around 1mln acres of natural forest concessions and associated manufacturing facilities in Gabon and Mozambique, said the increased revenues were achieved without increasing administration expenses.

SDX Energy PLC (LON:SDX) has announced a significant 35% increase in reserves at the South Disouq gas project in Egypt. The company owns 55% of South Disouq, which came online last year with ‘first gas’ achieved in November. A new assessment of the field’s reserves by consultant Gaffney, Cline & Associates (GCA) shows gross proved plus probable (2P) reserves increasing to 86bn cubic feet of gas, up from a prior figure of 66bn cubic feet.

The chairman of Red Rock Resources PLC (LON:RRR) has responded positively to proposed production expansion plans at the Tshipi manganese mine in South Africa. Tshipi is 49%-owned by Jupiter Mines Ltd (ASX:JMS), a company in which Red Rock holds just over 17mln shares, or 0,87%. The potential 50% increase represents, said Bell, “one of a number of encouraging developments at Jupiter, which continues its drive to improved efficiencies and stringent cost control.”

Verona Pharma PLC (LON:VRP, NASDAQ:VRNA), the respiratory diseases treatment developer, has created a new position: vice-president of Capital Markets Strategy & Investor Relations. David Moskowitz, who held similar positions at Trovagene and Biocept, has been appointed to the newly created role.

BATM Advanced Communications Ltd, (LON:BVC) announced that Ador Diagnostics, the firm’s subsidiary focused on the development and marketing of unique in-vitro molecular diagnostics solutions, has received its first commercial order from a leading Italian distributor of molecular biology and genomics products. In a statement, BATM – a leading provider of real-time technologies for networking solutions and medical laboratory systems – said that, under the agreement, Ador will deliver its new NATlab reader and cartridges for the identification of meningitis in the second half of 2020.

OptiBiotix Health PLC (AIM: OPTI) has announced a significant deal with one of the leading retailers of health supplements. Holland & Barrett, with over 1,300 stores in 16 countries, will stock the company’s weight management product SlimBiome. OptiBiotix said the international chain was an “ideal partner” because of its “knowledge and experience in marketing functional food supplements”.

Drug discovery company C4X Discovery Holdings PLC (LON:C4XD) expects to see further commercial traction and the advancement of its existing portfolio in 2020. In the company’s results statement covering the year to the end of July 2019, Clive Dix, the chief executive officer of C4X, said it was a year of building the drug discovery portfolio and advancing the drug discovery programmes to create a sustainable pipeline of potential revenue-generating assets.

Oil and gas contractor ADES International Holding PLC (LON:ADES) has announced a notable new contract renewal, securing the ADMARINE 262 rig with an important client in the Middle East. ADES, in a statement, noted that the new deal is set with a higher daily rate and the renewal would be for five years starting after April following on from the expiry of the current contract.

Landore Resources Ltd (LON:LND) has boosted the NI 43-101 resource at the BAM Gold project to just over 31mln tonnes of ore grading 1.02 grams per tonne gold. That gives a total of 1.015mln ounces of gold in the ground. 747,000 ounces is in the indicated category.

United Oil & Gas PLC (LON:UOG) has received formal technical environmental approval from the Italian Environmental Ministry for the development of the Selva Gas field.

Mineral & Financial Investments Ltd (LON:MAFL) has told investors that its 75% owned associate Redcorp Empreedimentos Mineiros expects to publish a preliminary economic assessment (PEA) of the Lagoa Salgada polymetallic project, in Portugal, later this month. In a statement ahead of its AGM, on 27 January, MAFL noted that the PEA had initially been anticipated by October 2019.

NQ Minerals PLC (NEX:NQMI) (OTCQB: NQMLF) has signed a deal with Bass Metals Ltd (ASX:BSM) to secure 100% of all the mining and exploration rights at the main 1,695 hectare Hellyer mining lease. Bass will surrender its long standing Sublease Agreement over Hellyer’s underground base metals rights. NQ has also acquired 100% rights to the 46 square kilometre Mt Block permit, which surrounds the Hellyer Mining Lease.

Crossword Cybersecurity PLC (LON:CCS) has appointed a new group sales director and a chair for its consulting subsidiary as part of plans to drive growth in 2020. The AIM-listed firm said the new sales director, Sean Arrowsmith, will be responsible for both products and consulting sales activity, inheriting a sales pipeline for the company’s Rizikon Assurance risk product worth over £3mln across 100 companies. Meanwhile, Robert Coles will be taking on the role of non-executive chair of Crossword’s consulting subsidiary and is currently serving as chair of the company’s advisory board.

Mkango Resources Ltd. (LON:MKA)(CVE:MKA) has appointed Tim Slater as interim chief financial officer. Slater is currently managing director of Harmer Slater which provides CFO, accounting and regulatory compliance to Aim and Toronto Stock Exchange-listed companies. He has previously served as interim CFO for several Aim and Venture Exchange-listed companies.

Tekcapital PLC (LON:TEK) has appointed former UK Minister for Universities and Science Lord Willetts to the board. He was a minister from 2010 to 2014 and became a member of the House of Lords in 2015.

Summit Therapeutics PLC (LON:SUMM) (NASDAQ:SMMT) said it has today launched, an online resource for patients with C. difficile infection (CDI) and their caregivers. The group said the site provides information about CDI, the role of the microbiome in CDI and Summit’s ongoing Phase 3 clinical trials of its investigational precision antibiotic, ridinilazole. Glyn Edwards, CEO of Summit commented: “With this online resource, we hope to provide those diagnosed with CDI and their caregivers with an understanding of factors pertinent to the choice of therapy, as well as information about the opportunity to be involved in our Ri-CoDIFy clinical trials evaluating ridinilazole for CDI.” The company said the Ri-CoDIFy clinical trials are expected to enrol up to 1360 patients across sites in North America, South America, Europe, Australia and Asia.

Horizonte Minerals PLC (LON:HZM) shares declined on Tuesday as a major holdings notification revealed that investor Richard Griffiths, and his controlled undertakings has reduced his holding in the company to less than 3%, down from 3.97% previously.