Sirius Minerals PLC (LON:SXX) has confirmed that it has received a premium-priced takeover offer from Anglo American plc (LON:AAL), and, it is now in advanced talks with the FTSE 100-listed miner. The offer is pitched at 5.5p per share, which is a 34.1% premium to yesterday’s closing price of 4.1p. In a statement released after the market close on Tuesday, Sirius’s management team said it would be prepared to recommend an offer at that price.

Midatech Pharma PLC (LON:MTPH) (NASDAQ:MTP) has hailed the positive results from a study assessing the potential to deliver one of its drugs via an injection under the skin rather than into the muscle. MTD201, which is being developed to treat carcinoid cancer and the growth hormone condition acromegaly, was able to maintain the correct levels of plasma octreotide over six to eight weeks using this subcutaneous method, researchers found.

Shield Therapeutics PLC (LON:STX) has signed an exclusive agreement worth up to US$63mln for its iron deficiency treatment Feraccru to be sold in China. The deal with ASK Pharm (Beijing Aosaikang Pharmaceutical), covers China, Hong Kong, Macau and Taiwan and will involve an upfront payment of US$11.4mln and up to US$51.4mln in milestone and royalties. ASK Pharm will also pay for the marketing authorisation process and commercialising of Feraccru, which is branded as Accrufer in the US.

Avacta Group PLC (LON:AVCT) has set up a joint venture to develop new cell and gene therapies using its Affimer proteins. The new JV with Daewoong Pharmaceutical Co will specifically target the development of a new class of mesenchymal stem cells (MSCs), multipotent cells where functions can include being agents for the treatment of autoimmune and inflammatory diseases.

Eden Research plc (LON:EDEN) has signed a one-year exclusive evaluation agreement with Corteva Agriscience. The American giant, valued at US$21bn, wants to assess the potential of the UK biopesticides specialist’s encapsulation technology, focusing on formulations for seed treatments.

ADM Energy Plc (LON:ADME) said it has now completed the fundraising it announced on 30 September 2019, which in total raised approximately £412,000, with the final stage raising £150,360 via an issue of 2,148,000 new ordinary shares at a price of 7p each to Zark Capital Limited. Following the issue, Zark will hold 6,000,000 ordinary shares, representing 9.7% of ADM’s issued share capital.

OptiBiotix Health PLC (LON:OPTI) said a human study for a new food supplement containing its LPLDL probiotic has shown it “can reduce high blood pressure”. The AIM-listed company’s ProBiotix and Italy’s Nutrilinea carried out a three-month study of 40 patients by the Center of Diabetes and Metabolic Diseases at the University of Pavia and Fondazione IRCCS Policlinico San Matteo in Italy.

Directa Plus PLC (LON:DCTA) is to trial its graphene-enhanced asphalt Gipave at Rome’s Fiumicino airport. Gipave will be tested for six months on the airport’s Alpha taxiway, which handles intercontinental aircraft such as Boeing 777s and Airbus A380s.

Rosslyn Data Technologies PLC (LON:RDT) said it has won two large contracts for delivery of Knowledge Capture, part of its information management suite of products, with a minimum combined contract value of £0.9mln over their minimum term. In a statement, the leading global big data technology company noted that the latest contract wins add to a growing list of multi-national clients for both the group’s RAPid supply chain analytics and information management solutions, adding £200,000 to the company’s annual recurring revenue.

AdEPT Technology Group PLC (LON:ADT) announced that it has delivered network services to more than 100 hospital and specialist care sites as part of a government contract with the NHS. AdEPT was contracted in 2018 to improve network and bandwidth capacity, to allow for financial savings and better access to clinical systems, after the previous connection managed by BT Group PLC (LON:BT.A) was deemed obsolete.

Impax Asset Management Group PLC (LON:IPX) has seen strong inflows of new money in the first three months of its current year. The sustainable investment specialist said funds under management rose 7% to £16.1bn in the quarter to December with £771mln of new funds and a £289mln gain from market movements.

Ormonde Mining plc (LON:ORM) has entered an agreement to sell its 30% stake in the Barruecopardo tungsten mine in Spain for around £5.1mln (€6mln). Mike Donoghue, chairman and interim managing director of the AIM-listed miner, said that while the disposal would come as a “disappointment for many shareholders”, the mine had encountered significant setbacks during ramp-up operations which had left it seeking further funding.

Assays from recent drilling at the Bonya tungsten and copper deposit in Australia have further underlined its potential according to Thor Mining PLC (LON:THR). Thor (40%) is the operator of a joint venture with Arafura (60%) and is drilling to establish Bonya as a source of ore to extend the life of its nearby Molyhil project in Australia’s Northern Territory.

Nektan PLC (LON:NKTN) has sold its UK B2C business for £200,000 as part of its restructuring plans. In an announcement after the close on Tuesday, the online gaming platform operator said the B2C business was sold by administrators to Grace Media Limited, and the firm had now entered a B2B partnership with Grace Media to facilitate continued delivery of its B2C services to its white label partners, through which it will receive monthly royalties

Genel Energy PLC (LON:GENL) on Wednesday confirmed the receipt of US$6.7mln in oil payments from the Kurdistan Regional Government (KRG). In a statement, the Iraq-based crude producer reported that the partners in the Taq oil field were paid US$6.7mln gross for oil sales in August 2019, and, its 44% net share amounted to US$3.6mln.

Anglo African Oil & Gas PLC (LON:AAOG) has released a statement informing investors that it has received notice of a potential claim against the company from a former energy advisor, Askell Limited. In a brief statement, the small-cap oiler said: ““AAOG believes the Askell claim is without merit and the company intends to defend the claim vigorously.”

W Resources PLC (LON:WRES) has announced the appointment of Oscar Marin Garcia as a non-executive director of the company with immediate effect. The group noted that Garcia has over 20 years’ experience, specialising in retail business in the Extremadura region of Spain and managing family office investments, and is co-founder and CEO of Lider Aliment, SA, a €200mln sales family-owned company. W resources pointed out that Garcia has a beneficial interest in 114,655,600 ordinary shares, representing approximately 1.8% of the company’s share capital.

Malvern International PLC (LON:MLVN) said that, further to its announcement on 23 December 2019, the sale of its Malaysian business to AAA Management Science Academy PLT for a total cash consideration of MYR 400,000 (approximately £75,000), payable over a 13 month period, has duly completed. Sam Malafeh, CEO of Malvern, commented: “We are delighted to have completed this transaction, as we can now bring greater focus to growing our UK and Singapore operations.”

Seeing Machines Ltd. (LON:SEE) said it, has collaborated with BMW Group to integrate its FOVIO driver monitoring technology into the BMW i Interaction EASE. It noted that this integration will be featured at the CES 2020 technology show in Las Vegas at the BMW booth Tech East Outside Area. The firm noted that BMW i Interaction EASE leverages Seeing Machines’ technology as a component of their innovative HMI (Human-Machine Interface) concept, visualized through a windshield projected Head-up Display (HUD). It added that Seeing Machines’ SVP of Fleet and Human Factors, Dr Mike Lenné, will also be conducting daily presentations on BMW’s CES booth from Wednesday through Friday.

Victoria Oil & Gas PLC (LON:VOG) announced that it has terminated its broker services agreement with GMP FirstEnergy. Shore Capital Stockbrokers Limited is now the company’s sole broker and Strand Hanson Limited continues to act as the company’s Nominated & Financial Adviser, the group said.

Ferro-Alloy Resources Limited (LON:FAR), the vanadium mining and processing company with operations based in Southern Kazakhstan, announced that its ordinary shares have been listed today on the Astana International Exchange (AIX) in Kazakhstan. The group said the shares will be traded under the ticker FAR with quotation and settlement in US dollars, and will be fully fungible between shares traded on the London Stock Exchange. Nick Bridgen, CEO, commented: “We are very pleased to be admitted to listing on the AIX. We see the AIX as strong platform that will allow the Company to capture interest from investors who we expect to be encouraged by the AIX’s use of the English language and English law, and its compatibility with the rules of the London Stock Exchange.”

Bluebird Merchant Ventures (LON:BMV) announced that its Annual General Meeting, held on 28 December 2019 in Jersey, all resolutions were duly passed.