Synairgen PLC (LON:SNG) said it has received approval to launch a phase II clinical trial of its lead drug in patients with COVID-19. SNG001 is an inhaled formulation of interferon-beta-1a and is currently being developed to treat people with chronic obstructive pulmonary disease (COPD) that also have respiratory viral infections.

Ergomed PLC (LON:ERGO) shares jumped on Wednesday as the firm revealed it is providing clinical research services for a study in Italy for the treatment of patients with coronavirus (COVID-19). In a statement, the AIM-listed company which is focused on providing specialised services to the pharmaceutical industry, today announced the initiation of a study of siltuximab, an interleukin (IL)-6 targeted monoclonal antibody, for the treatment of patients with COVID-19 who have developed serious respiratory complications.

Westminster Group PLC (LON:WSG), a leading supplier of managed services and technology-based security solutions worldwide, has provided another update on the current effects of coronavirus on its business. The company said that whilst its West African airport operations have been seeing record passenger number over the past few months, the announcements this week that governments in many parts of the world are restricting and cancelling flights in response to the coronavirus (COVID-19) pandemic, will have an inevitable impact on revenues from this part of our operations.

Europa Oil & Gas Holdings PLC (LON:EOG), Union Jack Oil PLC (LON:UJO) and its partners described the Wressle oil field development project, onshore UK, as “economically robust in the current low oil price environment”. In a statement, the partners respectively conveyed the findings of the operator, Egdon Resources Plc’s (LON:EOG) updated model which estimated a US$17.62 per barrel break-even oil price for the project.

IQ-AI Limited (LON:IQAI) said its Imaging Biometrics (IB) subsidiary, a provider of ready-to-use software to the healthcare industry, had its software featured in the top-award-winning article of a paper. The article was published in the March 2020 issue of the American Journal of Neuroradiology, which assigned it the Lucien Levy Award, recognising it as the best original research paper accepted in 2019. 

Cello Health PLC (LON:CLL) shares moved higher on Wednesday as the AIM-listed firm reported higher revenues and profits for 2019 alongside an increased dividend. For the year ended 31 December, the healthcare advisory firm reported a headline pre-tax profit of £13.1mln, up 6.6% on the prior year, while net revenues jumped 6.7% to £107.6mln.

Live Company Group PLC (LON:LVCG) has inked an agreement with The Copyrights Group Limited to produce a BRICKLIVE tour themed around the Paddington Bear brand. Under the agreement, the media firm’s subsidiary Brick Live International (BLI) will produce and exhibit a themed trail of Paddington Bear models around the UK, Ireland and the Channels Islands, with the first tour due to launch later in 2020.

Integumen PLC (LON:SKIN) said it has signed a three-year deal with Modern Water worth a headline £3.12mln. It will manufacture and provide logistical support for the latter’s monitoring reagent consumables. In the same announcement, Integumen said it was doubling the size of Labskin Laboratories in York in the second quarter to 6,000 square feet, adding six more laboratory rooms in order to meet growing demand.

Integumen also said it has been notified that its chief executive, Gerard Brandon has today acquired 1,100,000 ordinary shares in the company at a price of 0.83p each. The group said that Brandon’s resultant shareholding is 51,299,012 shares, representing 4.78% of Integumen’s issued share capital.

Caledonia Mining Corporation PLC (LON:CMCL) reported 2019 revenue of US$75.8mln, up from US$68.4mln, as operations at the Blanket mine marked new production records for the year. The gold producer said some 55,182 ounces of gold were produced in the twelve months ended 31 December 2019, up from 54,511 ounces, meanwhile, output in the fourth quarter set a new record of 16,876 ounces.

Savannah Resources PLC (LON:SAV) is involved in advanced negotiations with several counterparties regarding offtake agreements, services and strategic partnerships for its Mina do Barroso project. “Investors should be assured that in the board’s opinion the groups we are negotiating with represent ideal counterparties for the project and we are confident of formalising commercial terms with them in a timely manner,” said David Archer, chief executive. In the meantime, Savannah will focus on completing the pre-development phase of the lithium project.

Curtis Banks PLC (LON:CBP) said a good response to its new SIPP product helped self-administered pension specialists boost revenues and profits in the year just ended. The group’s revenue, which comes largely from pension fees, rose by 6% to £48.9mln while better margins helped profits increase by 11% on an underlying basis to £13.4mln.

Curzon Energy PLC (LON:CZN) has announced the signing of a letter of intent which envisages the 100% acquisition of the London Critical Metals Market (LCMM).  The LCMM aims to be the “first unified global metals trading exchange for critical metals that have few or no direct investment or trading options elsewhere in the world,” Curzon noted.

Jersey Oil and Gas PLC (LON:JOG) told investors it is fully funded as it continues to progress the Greater Buchan Area (GBA) field development, which will be concept selection work. In a statement addressing market weaknesses in light of the coronavirus (COVID-19) pandemic, the company said that it has no debt and, on current plans, it has sufficient working capital through to the end of 2021.

Vast Resources PLC (LON:VAST) has confirmed the departure of a shipment containing equipment from China bound for Romania. The company said the equipment for use at its Baita Plai polymetallic mine in Romania is presently expected to arrive at the port of Constanta by 23 April, according to the shipping company. A further 3-4 shipment containers are due for departure later this week, Vast noted.

Genel Energy PLC (LON:GENL) chief executive Bill Higgs told investors that its producing assets are profitable with oil prices of US$30 per barrel, and, along with its robust balance sheet, this supports a material dividend as well as investment in growth. That said, a pair of statements on Wednesday detail impacts of the coronavirus and a downgrade of reserves, mainly associated with ‘end of life’ decline at the Tawke field.

Motif Bio PLC (LON:MTFB) said it has had no luck in finding a buyer for its legacy assets, including the phase III antibiotic iclaprim, and the cash shell warned “there can be no assurance” of a deal. While it is eking out what remaining funds it has its financial reserves are only likely to last until May, investors were told in a statement. In the meantime, it is looking for a reverse takeover candidate with a July 28 deadline to broker such a transaction.

accesso Technology Group PLC’s (LON:ACSO) chief executive has hailed “positive momentum” in the firm’s key performance metrics as it aimed to build its recurring revenue base in the coming year. In a statement accompanying accesso’s full-year results, Steve Brown, CEO of the electronic queuing specialist, said transactional revenues were continuing to “grow double-digit” and now accounted for 80% of total revenues while the group had also “realised strong results in eCommerce transactional revenue and virtual queuing sales”. Looking ahead, accesso said trading in the first two months of 220 had been “in line” with management expectations, although since mid-March the outbreak of coronavirus has been “significantly impacting” guest visitation across its client’s sites, impacting the firm’s transactional-based revenues.

Immotion Group PLC (LON:IMMO) has said it is reducing operating costs and has “a healthy cash balance” as it joins other firms in supporting itself against the effects of the coronavirus outbreak. In an update on Tuesday afternoon, the virtual reality (VR) firm said over the last few days trading at a number of its sites had been “significantly impacted” as attendee numbers fell and a number of its partners reduced opening hours or, in some cases, closed.

Collagen Solutions PLC (LON:COS) has warned that it expects its full-year loss will be materially greater than anticipated due to increased costs from a development and manufacturing contract which has taken longer than originally anticipated and also flagged up coronavirus (COVID-19) impact concerns. In a trading update for the year ended 31 March 2020 and a statement regarding the COVID-19 outbreak, the AIM-listed developer and manufacturer of biomaterials for the enhancement and extension of human life said the related accounting treatment requires a one-time write-down of around £900,000 recognising the full loss over the life of the development portion of the contract only.

Oracle Power PLC (LON:ORCP) has announced the appointment of senior coal mine manager Glen Lewis as a non-executive director of the company with immediate effect. The group noted that throughout his career Lewis has focused on operational mine management and developed a number of significant coal deposits, including United Colliery and Dartbrook Coal in the Hunter Valley in Australia. It said he was the Operations Manager at Oceanic Coal following its acquisition by Xstrata Coal in 1999 and rose to become General Manager of Operations at Xstrata Coal in 2003. Lewis was appointed Managing Director of NuCoal Resources Ltd (ASX:NCR) in 2010, stepping down in 2017 to focus on advisory opportunities in the public and private sector.  Mark Steed, Oracle Power’s chairman commented: “Oracle is making this appointment now as we look to the ultimate development of Block VI in Pakistan, where we believe his experience will prove a significant asset to the Company and provide genuine technical asset-level understanding, complementing the expertise already within the Company and amongst its project partners.”

Eden Research plc (LON:EDEN), the AIM-quoted company that develops and supplies breakthrough biopesticide products and natural microencapsulation technologies to the global crop protection, animal health and consumer products industries, announced that at its General Meeting held on Wednesday, all resolutions proposed were duly passed by shareholders.

Walls & Futures REIT PLC (LON:WAFR) the ethical housing investor and developer announced that for the calendar year ending 2019, its portfolio outperformed its benchmark, the MSCI UK Residential Index, by 23.0% to 4.4%. Joe McTaggart, CEO of Walls & Futures commented: “We are extremely pleased with the portfolio performance. The value growth created further validates our investment strategy of originating our investments and real estate development as opposed to acquiring ready-made portfolios from third parties.”