Sareum Holdings PLC (LON:SAR), the specialist drug development company, has described results from studies of two of its small molecule inhibitors to combat lupus as “encouraging”. The company, which is focused on delivering targeted small molecule therapeutics to improve the treatment of cancer and autoimmune diseases, said that results have been published for its small molecule dual tyrosine kinase 2 (TYK2) and Janus kinase 1 (JAK1) inhibitors in disease model studies of systemic lupus erythematosus (SLE) by its collaborator, SRI International. Sareum entered into a co-development agreement with SRI International in April 2013 to develop TYK2 inhibitors in autoimmune diseases. Sareum retains commercialisation rights for these and other TYK2 inhibitors.

Thor Mining PLC (LON:THR) (ASX:THR) has revealed additional positive results from the initial hydrogeological drilling program at the Kapunda ISR (Insitu Recovery) copper project carried out by EnviroCopper Limited. The group said the hydrogeological testing program was successful, with the tracer test showing fluid movement from well to well in a relatively short time period, providing the potential for cost-saving through reducing the number of wells for optimum production. Thor Mining holds a 25% interest in EnviroCopper Limited with rights to increase that interest to 30%.

Bahamas Petroleum PLC (LON:BPC), the oil and gas exploration company has announced the appointment to its board, with immediate effect, of Peter Cannell, as an alternate director to its non-executive chairman, Bill Schrader. The appointment is solely for the purpose of matters relating to the company’s Annual General Meeting (AGM), taking place at 10.00am BST on Friday, at the company’s registered office at IOMA House, Hope Street, Douglas, Isle of Man, IM1 1AP . As such, Cannell’s appointment will terminate following the closing of the AGM. The other existing members of the Board are unable to attend the AGM as a result of restrictions and advice relating to the coronavirus (COVID-19) pandemic. Cannell is an Advocate and Chartered Governance Professional at Quinn Legal, which has acted as BPC’s Legal Counsel in the Isle of Man for 2 years.

In a subsequent statement, Bahamas Petroleum announced that at the AGM held on Friday, all resolutions were passed with the exception of Resolution 3 which had proposed the expansion of the company’s available pool of employee options for future allocation at the discretion of the board. Acknowledging the lack of shareholder support for this resolution at this time, the company said it will seek to develop alternative incentivisation strategies, so as assist in ongoing processes to recruit, incentivise and retain high-quality employees.

Berkeley Energia Limited (LON:BKY) said the Board of the Nuclear Safety Council (NSC) in Spain has indicated authorisation for the uranium concentrate plant at Salamanca should be extended. The initial authorisation for the uranium concentrate plant as a radioactive facility was granted in September 2015. Berkeley Energia said while it has not received formal notification of the decision, the outcome of the NSC board meeting was posted on its website yesterday (23 July).

Integumen PLC (LON:SKIN) said its subsidiary, Labskin has launched the world’s first remote clinical skin trials platform. The AIM-listed group said the platform will harvest a human volunteer’s skin and transport it to the Labskin laboratory to be transplanted onto laboratory-grown skin, creating an exact replica of the human volunteer’s skin microflora without them leaving their home. Integumen also said another subsidiary, software and artificial intelligence (AI) group Rinocloud, has built a remote clinical skin trial platform which allows trials to happen ethically, efficiently with all protocols being followed and distantly controlled, with data stored according to GDPR guidelines.

Sativa Group PLC (LON:SATI) said it has launched a new cannabidiol (CBD) and Vitamin D product range under its Goodbody Wellness brand. The CBD group said the products will be the only range in the UK to offer two flavours and three CBD strengths of 5%, 10% and 20% CBD and Vitamin D bottled within olive oil. Sativa said its brand positioning has been strengthened by the new products and the additional benefits associated with combining CBD and Vitamin D.

Tissue Regenix Group PLC (LON:TRX) has started the first phase of its planned manufacturing capacity expansion programme in San Antonio, Texas. The regenerative medical devices company said the capacity expansion represents a key element of its commercial development plan. The first part of the multi-phase expansion programme is expected to take about six months to complete and will include the development of operational capabilities in the new 21,000 square feet building to house freezers and distribution functions that will free up space for additional sterile packaging clean rooms to be built in the existing facility.

Vast Resources PLC (LON:VAST) has updated investors on its operations at the Baita Plai polymetallic mine, in Romania, where it has now received to site all awaited containers of equipment required for the continued development of the mine. Vast said it now intends to start underground production next week and it expects first concentrate production will take place in August. Additionally, the company gave details of its metallurgical testing programme which has provided encouraging results for copper and zinc, while lead and molybdenum tests are ongoing.

AFC Energy PLC (LON:AFC) has told investors that 2020 continues to be a transformational year for the international hydrogen economy. The company, in its interim results statement, highlighted its own progress which included the successful launch of its electric vehicle (EV) charging solution, the start of product development for the HydroX-Cell(L)160 system and – in the current period – a £31.6mln cash raise to fund further development. “With unprecedented investment into the sector from both private and public institutions, AFC Energy remains focussed on the consolidation of its position as a leading developer of alkaline, zero-emission fuel cell systems,” Adam Bond, AFC chief executive said in the results statement.

Anglo Pacific Group PLC (LON:APF) (TSE:APY), the mining royalties company, said it is expecting a better second-half performance as demand for minerals recovers with the easing of the coronavirus (COVID-19) pandemic. Funds received or receivable from the group’s underlying royalty related assets – what Anglo calls the portfolio contribution – declined to between £18.5mln and £19.0mln in the first half of 2020 from £25.5mln in the preceding six months and £33.31mln in the first half of 2019.

Landore Resources Ltd (LON:LND) has highlighted continuing progress at the BAM gold deposit as it posted its full-year results, and separately revealed plans for a share consolidation. A recent funding move has set the explorer up for new drilling. In June 2020, Landore raised £2.8mln, issuing 414mln shares at a price of 0.675p, to pay for 14,000 metres of drilling in total. In terms of financial results, the pre-revenue company reported a £2.14mln loss for the year ended December 31, 2019, with £107,688 of cash. Landore also announced plans to consolidate its share capital by reducing the number of shares in issue by a multiple of 20. Every twenty shares held by investors will be transferred into one new share under the plan, which requires shareholder approval.

US Oil & Gas PLC (LON:USOP) has told investors that it is expecting to land a permit for well drilling at the Eblana project in eight to twelve weeks’ time. The oil and gas explorer, in a statement, said it is positioned operationally to drill on the award of the permit. “For some time, the company has been fully prepared to drill Eblana-9 as soon as the necessary permits are awarded,” chief executive Brian McDonnell said in an operations update.

Caledonia Mining Corporation PLC (LON:CAL) announced that it has entered into an ‘At the Market’ (ATM) sales agreement with Cantor Fitzgerald under which the company may, at its discretion from time to time, sell up to US$13mln worth of shares. Any sales of shares would occur by means of ordinary brokers’ transactions or block trades, with sales only being made on the NYSE American at market prices. Caledonia expects to use the amount of any net proceeds from the sales for investment in the construction of a solar power plant to supply electricity to Blanket Mine in Zimbabwe. The ATM Sales Agreement is not a formal placing and any potential sales of new shares are not underwritten by the sales agent.

Tiziana Life Sciences PLC (LON:TILS) (NASDAQ:TLSA), a biotechnology company focused on innovative therapeutics for oncology, inflammation and infectious diseases, said it has allotted and issued 88,580 ordinary shares of 3 pence each credited as fully paid in respect of an exercise of 88,580 warrants at a price of 93p per share, yielding 82,379 in cash proceeds for the company.

Premier African Minerals Limited (LON:PREM) has announced that Regent Mercantile Holdings Limited has elected to convert their loan plus accrued interest in the amount of US$390,040.92 (£305,836.77) in accordance with the terms of the loan agreement as announced on June 21, 2019, into new ordinary shares in the company and it has therefore issued 431,241,920 new ordinary shares to Regent at an issue price of 0.07092p per share. George Roach, Premier African’s CEO, commented: “Regent invested in this loan agreement with the stated intention to convert the loan into Premier shares at a time Regent considered appropriate and in pursuance of their desire to be a long term supportive shareholder. I am appreciative of this statement of support and their continued association with Premier as a shareholder.” The issue of the shares will also see the termination of the security held by Regent over 350,000 shares of Circum Minerals Limited.

Greatland Gold PLC (LON:GGP), the AIM-listed precious and base metals exploration and development company, has announced the exercise of options and sale of shares by Gervaise Heddle, its chief executive officer. The company said it has received a binding option exercise notice from Heddle for 5,000,000 options at 2.0p per share for a total consideration of £100,000. Greatland added that it has also been notified that Heddle sold 3,500,000 ordinary shares in the company at a price of 14.6p each for a total consideration of £511,000 on July 23, 2020. Following the option exercise and sale of shares, it noted that Heddle has an increased holding of 76,750,000 ordinary shares, representing 2.0% of the issued share capital of the company. Additionally, he has 27,000,000 share options at various strike prices.

APQ Global Ltd. (LON:APQ) has said the company’s auditor, BDO, has advised that, due to personnel restrictions during the coronavirus (COVID-19) pandemic, it requires further time to complete its audit of the group’s 2019 results. The company said it now expects to publish its 2019 results by August 31, 2020. It continues to expect to report its interim accounts for the first half of 2020 around the same time. APQ Global also announced that as at the close of business on June 30, 2020, its unaudited book value per ordinary share was 31.70 US cents, equivalent to 25.65p.

Immotion Group PLC (LON:IIMO) said it has been advised that, following the acquisition of the investment activities of Cavendish Asset Management by Stonehage Fleming, that Cavendish Asset Management no longer has a notifiable interest in Immotion Group and that Stonehage Fleming now holds 33,035,010 shares in the company, representing 8.7% of the issued share capital, as a result of that transaction.

Silence Therapeutics PLC (LON:SLN)) a leader in the discovery, delivery, and development of novel RNA therapeutics for the treatment of serious diseases with unmet medical need announced that at its general meeting held on Thursday, July 23, 2020, all resolutions set out in the notice of meeting were duly passed on a poll.

Remote Monitored Systems PLC (LON:RMS) said that at the company’s annual general meeting hold on Friday all resolutions were passed.

Live Company Group PLC (LON:LVCG) announced that at the group’s annual general meeting held on Thursday all resolutions were duly passed.

Arkle Resources PLC (LON:ARK), the Irish gold and zinc exploration and development company, said that at the company’s annual general meeting, held on Friday, Patrick Cullen retired as a director in accordance with Article 89 and has not been re-elected, and all other resolutions were duly passed. It also said an updated presentation is now available on the company’s website and may be accessed here.

Tally (PRIVATE) has said it will hold a live shareholder Q&A with the two co-founders, Cameron Parry and Ralph Hazell on the online Tally Community, Tuesday, July 28, 2020, from 7pm-8pm. This exclusive shareholder session will be later in the day after the ‘public’ Q&A on the product from 6pm which anyone can join, however, shareholder and company-related matters will only be responded to in the shareholder session. If you have not signed up to the shareholder section of our community you can sign up here.