A close up of a magnifying glass rests on top of a bar graph that shows declining sales or performance over a quarterly basis. The image is photographed using a very shallow depth of field.

Tiziana Life Sciences PLC (LON:TILS, NASDAQ:TLSA) has submitted a patent application covering the potential use of nasally-administered and orally taken Foralumab for the treatment of COVID-19 either alone or in combination with other antiviral drugs. The methods of delivering the fully human anti-CD3 monoclonal antibody (mAb) could potentially modulate or stimulate the immune system to suppress cytokine storms and therefore reduce respiratory failure in coronavirus patients, the company said. Its researchers believe its combination with other anti-viral drugs could improve efficacy.

Thor Mining PLC (LON:THR) (ASX:THR) has revealed that there is visible gold from sample panning of the second phase of gold, nickel, and chromium geochemical sampling at the 100% owned Pilbara Goldfield tenements (E46/1262 and E46/1190) in Western Australia. Among the highlights, 17 of the 32 stream sediment samples had visible gold in panning, while two of the 2019 sample sites (19PST22 and 19PST32) had visible gold in multiple follow-up stream sediment samples, and samples 20PST04 and 20PST24 returned 13 and 11 grains respectively from panning. Mick Billing, Thor Mining’s executive chairman commented: “This appears to be a highly successful follow-up, to the previous, very successful, sampling program.”

ReNeuron Group PLC (LON:RENE)  has announced that the US Patent and Trademark office (USPTO) has completed its examination of the company’s patent application (14/379,239), entitled: “Phenotype profile of human retinal progenitor cells” and has issued a notification of allowance for the issuance of a patent. In a statement, the UK-based global leader in the development of cell-based therapeutics said the allowed patent protects the composition of the company’s hRPC cell-based therapeutic candidate for retinal diseases, cultured under specific conditions to enhance function and identifiable by the presence and absence of specific cell surface markers. This notification of allowance in the US adds further intellectual property protection to the hRPC technology, which already has patent protection in a number of other major territories including Europe, Japan and Australia, it added.

SkinBioTherapeutics PLC (LON:SBTX) has updated investors on the progress of its cosmetic skincare programme and a psoriasis food supplement trial. The AIM-listed firm said Sederma, its partner in the cosmetics programme and a division of Croda International PLC (LON:CRDA), has successfully replicated the lysate manufacturing process and achieved the same performance from the company’s SkinBiotix technology and is now working to validate a scale-up of the manufacturing process at different volume levels. Meanwhile, the firm said in light of current restrictions on non-coronavirus related human studies, it has established a protocol for its ‘ self-managed’ psoriasis food supplement trial and was proceeding with the study.

Impax Environmental Markets PLC (LON:IEX) revealed on Thursday that it is to pay a first interim dividend for the 2020 financial year of 1.3p per ordinary share, and said it is the intention of its board to declare a final, or second interim, dividend towards the end of the first quarter of 2021. In a statement released after the London market close, IEX said that in order to be equitable to all shareholders, and following a similar consideration of paying last year’s (single) dividend as an interim rather than a later final, the board has decided that henceforth it will declare an interim dividend at the half-year stage, with a second dividend payable after the year-end.

Oncimmune Holdings PLC (LON:ONC) has announced that The European Respiratory Journal – a leading lung disease-focused scientific publication and flagship journal of the European Respiratory Society – has published the peer-reviewed results from the Early detection of Cancer of the Lung Scotland (ECLS) trial. The trial was delivered by the Universities of Dundee and St Andrews with NHS Tayside, and co-funded by Oncimmune, the Scottish Chief Scientist Office and the Scottish Government. The leading global immunodiagnostics group said the paper titled ‘Earlier diagnosis of lung cancer in a randomised trial of an autoantibody blood test followed by imaging’ – which is now available online and will be replicated in print before Q3 2020 – evaluates the effectiveness of Oncimmune’s EarlyCDT Lung test in reducing the incidence of patients presenting with late-stage lung cancer at diagnosis.

Collagen Solutions PLC (LON:COS) has reported that its year-to-date sales plus its confirmed order book are now over £4mln following the signing of two supply agreements in its first quarter. In an update on current trading accompanying results for the year ended March 31, 2020, the biomaterials and regenerative medicines firm also reported revenue of £900,000 for its first quarter, helped by a reduction in the impact of coronavirus experienced in the fourth quarter of the prior year, as well as a cash balance at the end of the period of £1.6mln. For the prior year, Collagen reported revenues of £4.46mln, down 1% year-on-year, alongside a pre-tax loss of £2.06mln compared to £1.79mln in the prior year.

MBH Corporation Plc (FRA:M8H) has expanded its construction arm with its fourth acquisition of 2020. GS Contracts (Joinery) Limited, a specialist in high-end hospitality and retail fit-out work, has joined the group for a consideration of £1.7mln in convertible notes and bonds. The payment includes the acquisition of a commercial property worth roughly £0.8mln as GS Contracts brings their own in-house production facilities.

Benchmark Holdings PLC (LON:BMK) said it has completed the sale of its vaccine manufacturing facility at Braintree in the UK to Cell and Gene Therapy Catapult for £16mln in cash. The aquaculture specialist said the sale forms part of a £100mln investment by the UK government to develop the Cell and Gene Therapy Catapult Manufacturing Innovation Centre to manufacture millions of doses of coronavirus vaccines per month.

NQ Minerals PLC (AQSE:NQMI) (OTCQB:NQMLF) (OTCQB:NQMIY) said it is “optimistic” for its prospects moving forward after reporting rising production from its Hellyer mine in the first part of 2020. In an outlook statement accompanying its results for the year ended December 31, 2019, the company reported that in the first quarter of 2020 it produced 8,127 tonnes of lead concentrate, up from 4,712 a year ago, while zinc concentrate rose to 4,609 tonnes from 3,015.

European Metals Holdings Limited (LON:EMH) (ASX:EMH) has highlighted “continued progress” at its Cinovec lithium and tin project in Czechia. In an update for the three months ended June 30, 2020, the AIM-listed firm said during the period a €29.1mln investment in Cinovec by conglomerate CEZ Group was completed and project work will commence immediately, while a preliminary mining permit for the project has also been granted relating to the eastern part of the deposit for eight years. The company is also in discussions with the Prague Stock Exchange regarding a proposed listing, adding that it has also arranged an interim funding facility to assist in financing new initiatives for ongoing operations.

Conroy Gold and Natural Resources PLC (LON:CGNR), the gold exploration and development company focused on Ireland and Finland, said it has received a notice to exercise warrants to subscribe for 1,358,333 ordinary shares at a price of 16p per ordinary share for which funds of £217,333 have been received by the company. The warrants were issued as part of the placing and subscription for new Ordinary Shares announced on February 18, 2020. The group added that proceeds from the exercise of the warrants will be used for general working capital purposes.

ADM Energy PLC (LON:ADME), a natural resources investing company, has announced the appointment of REYL Group to support the company with the development and financing of energy projects in Nigeria and West Africa. REYL Group is a Geneva-based banking group that manages assets in excess of 13.5 billion Swiss francs. REYL Group will advise ADM on financing structures for future projects including the acquisition of the interest in OML113 from EER (Colobus) Nigeria Limited, announced on 24 February 2020, and any follow-on agreements with Trafigura Pte Ltd pursuant to the memorandum of understanding signed with Trafigura on 3 February 2020. 

Enteq Upstream PLC (LON:NTQ) said it received notification on July 31, 2020, that its finance director, David Steel acquired 75,000 ordinary shares in the company at a price of 12p peach on that date.  Following this acquisition, the group noted, Steel has an interest in 1,526,741 Enteq ordinary shares, representing approximately 2.3% of the company’s issued ordinary share capital.

San Leon Energy PLC (LON:SLE), the independent oil and gas production, development and exploration company focused on Nigeria, has announced the appointment of Allenby Capital Limited as the company’s nominated adviser and joint broker with immediate effect. It also said that, following the acquisition of Whitman Howard Limited by Panmure Gordon & Co, it has appointed Panmure Gordon as its other joint broker with immediate effect.

Iofina PLC (LON:IOF), specialists in the exploration and production of iodine and manufacturers of specialty chemical products, has announced the launch of its new corporate website at www.iofina.com. The website will include current information for customers and investors, be mobile and tablet friendly, and will be continuously improved and updated.

Kodal Minerals PLC (LON:KOD), the mineral exploration and development company focused on its Bougouni Lithium Project in southern Mali, has announced that its annual general meeting (AGM) will be held at 12.00pm on August 27, 2020, at Prince Frederick House, 35-39 Maddox Street, London W15 2PP. As a consequence of the current measures implemented by the UK Government, shareholders will not be permitted to attend the AGM but are strongly encouraged to submit their votes by proxy as soon as possible. The company said it is intending to hold a webcast for shareholders after the AGM in the form of a presentation followed by Q&As.  Further details will be announced in due course.

finnCap Group PLC (LON:FCAP) has announced that annual general meeting (AGM) will be held at the company’s registered office address, 1 Bartholomew Close, London EC1A 7BL on Monday, September 21, 2020. It is planned to hold the AGM as a closed meeting and shareholders are not permitted to attend, due to the current coronavirus (COVID-19) pandemic. Given this, shareholders are strongly encouraged to vote by proxy in advance of the AGM. 

Coinsilium Group Limited (LON:COIN) has reported a sharp reduction in its full year losses alongside gains on its financial assets. For the year ended December 31, 2019, the blockchain investment and advisory firm reported a pre-tax loss of £258,943, narrowed from £982,034 in the prior year, while it also delivered a net fair value gain on its financial assets of £572,805 compared to a £188,781 loss in 2018.

KR1 PLC (LON:KR1) has swung to a profit in its latest full-year following an upswing in gains from its digital investments. For the year ended December 31, 2019, the cryptocurrency and blockchain investor reported a profit for the year of £1.33mln compared to an £8.34mln loss in the prior year, boosted by a £2.05mln unrealised gain on digital investments compared to a £12.7mln loss in 2018.

Metal Tiger PLC (LON:MTR) has highlighted a new quarterly activities report that has been published by Cobre Ltd (ASX:CBE), a company in which Metal Tiger holds a stake of about 18.8%. “This has been a strong quarter for Cobre with drilling continuing across the Perrinvale project, demonstrating significant high-grade copper-gold results,” said Michael McNeilly, chief executive of Metal Tiger. Separately, the company also entered into a further equity derivative collar financing arrangement in relation to its shareholding in Sandfire Resources (ASX:SFR).

AEX Gold Inc. (LON:AEXG) (CVE:AEX) saw its shares commence trading on the AIM market of the London Stock Exchange at 8000am BST on Friday under the ticker AEXG. The AIM debut of the independent gold company with a portfolio of gold licences in Greenland followed a fundraise which comprised a placing and direct subscriptions for an aggregate of 94,444,445 new common shares at a price of 45 pence per share or 77 Canadian cents per share, raising gross proceeds of £42.5 million (C$72.7 million), with the new shares represent 53.3% of the company’s enlarged share capital. AEX Gold also announced that Sigurbjorn (Siggi) Thorkelsson had joined its board as an independent non-executive director, and chair of the Audit Committee on July 27, 2020.

Bloomsbury Publishing PLC (LON:BMY said that payment of the intended final dividend of 6.89p for the year ended February 29, 2020, by way of bonus issue was overwhelmingly approved by shareholders at the company’s AGM on July 21, 2020. The company today announced that the reference share price for the bonus Issue is 216.80p. The bonus issue shares will be issued and admitted to trading on August 28, 2020. Further to the AGM Notice, no fraction of a bonus issue share will be issued.